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Thousands demonstrate in the bitter cold in Washington -- some against abortion, others in favor of abortion rights -- on the 30th anniversary of Roe v. Wade, the Supreme Court ruling that made abortion legal in the United States. NPR's Jacki Northam reports.

Researchers say they have used genetic engineering to create a mouse that is abnormally anxious and aggressive -- a strain that could help explain why some people are prone to anxiety or panic attacks. NPR's Jon Hamilton reports on new research published in the journal Neuron. Watch videos of normal mouse behavior, and the violent behavior of a genetically modified mouse.

President Bush uses his State of the Union speech to build a case for war with Iraq, but also addresses economic revival and health care reform. He says Secretary of State Colin Powell will go to the U.N. Security Council on Feb. 5 to explain the U.S. position on Iraq. Hear NPR's Don Gonyea, Michael O'Hanlon of the Brookings Institution and Rep. Nancy Pelosi (D-CA).

President Bush uses his State of the Union address to build a case for war with Iraq, but also outlines an ambitious domestic agenda for Congress, including health care reform and economic revival. He says Secretary of State Colin Powell will go to the U.N. Security Council on Feb. 5 to emphasize "the facts of Iraq's ongoing defiance of the world." NPR's Nancy Marshall reports.

Alan Cheuse reviews Dancer, a fictionalized biography of Rudolf Nureyev by Colum McCann. Dancer is published by Metropolitan Books.

In a mid-term report card, Secretary of State Colin Powell earns the highest grades among members of the Bush Cabinet, according to a National Journal study. Powell receives the only 'A' in the magazine's report card, which grades the department heads on such criteria as their influence within the administration. NPR's Bob Edwards interviews Jim Barnes, the weekly's chief political correspondent, about the report.

Confronted with the mess she's made at her startup Theranos, Holmes simply runs at the end of the Hulu show.

Many in the Latino immigrant communities of Los Angeles continue to celebrate Christmas through today, the Feast of the Epiphany. NPR's Mandalit Del Barco visits the elaborate and detailed homemade nativity scenes that decorate yards in East L.A.

NPR's Joe Palca reports on the challenge of proving a company's claim that a cloned baby girl has been born. The proof will require DNA samples. And the trickiest part may be ensuring that the samples truly come from the baby and her mother.

Mister Cartoon (AKA Mark Machado) runs a rapidly growing clothing and jewelry business from his East Los Angeles tattoo parlor. But his real claim to fame is his unique, Chicano street style tattoos. His work is a favorite among top music stars like Eminem. NPR's Michele Norris visits the artist in his studio -- see photos of Machado at work.