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For 25 years, Sub Pop has been putting out music that speaks to Seattle. Today, the music may not all be local, but the label's artists are mostly specialists who have perfected a certain style.

President Obama with Rose Garden appearance looks for major reset of problem-plagued rollout of his signature health care legislation

Gangsters in Karachi are a little different from the American variety. They often control armed groups linked to political parties. Uzair Baloch is known as the don of Karachi's Lyari slum. But ask him if he's a gangster, and he'll laugh. He says he's a politician and a social worker.

Republicans want to raise revenue by closing loopholes in the tax code instead of by raising rates. But tax breaks like the charitable deduction and the mortgage interest deduction come with interest groups willing to fight tooth and nail for them.

The infamous Boston mobster Whitey Bulger is on trial after decades of alleged crimes, including 19 murders. Weekend Edition Saturday Host Scott Simon talks with Dick Lehr, co-author of "Whitey: The Life of America's Most Notorious Mobster," about the trial.

The British-American actress co-stars opposite Eric Bana in the surveillance-state thriller Closed Circuit. She joins NPR's Robert Siegel to talk about playing a barrister, working with her celebrated Shakespearean father and being inspired by her opera-singer mom.

Patty Stonesifer once held a top spot at Microsoft. After that, she spent years at the helm of philanthropy giant the Gates Foundation. But this year, Stonesifer downsized. She's taken on a smaller-scale role as CEO of Martha's Table, a Washington, D.C., nonprofit that serves the poor.

Three years after bariatic surgery, most people experienced health improvements. Yet some people benefited much more than others. Figuring out those differences would help doctors and patients understand who should have surgery and who should avoid it.

Hanan Abu Qassem is one of a handful of female emergency medical technicians working at Palestinian soccer games. Stares and jeers don't faze her. "I'm anxious to be a very famous EMT," she says.

Fruity, sweet, spicy and salty all at once, this frenzied treat for your taste buds takes many forms — from sauces to seasonings to candy. And its journey from Asia to Mexico took hundreds of years.